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James W. Black

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I chose to study Medicine mainly under the influence of an elder brother, William, a graduate in Medicine at St Andrews some years earlier.

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James W. Black

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Half-jokingly, I asked what was wrong with me. So we made a deal: I would run his biological research provided I had a free hand to run my new project.

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James W. Black

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During my six years with them Dr Garnet Davey (subsequently Research Director) constantly supported me and, I have no doubt, fought many battles on my behalf to keep the initially controversial programme going.

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James W. Black

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Duncan brings brio and bravura to everything he does; and he is reliably my severest critic. Without him I would have made many more mistakes than I did.

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James W. Black

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Division for help and ended up being employed by them at their exciting new laboratories at Alderley Park, Cheshire.

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James W. Black

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By 1972, the H2-receptor antagonist programme was launched, cimetidine was in development and I was looking for a new project.

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James W. Black

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By 1963, I faced opposing pressures. I saw that the success of the beta-receptor antagonist programme would suck me more and more into the role of giving the young propranolol technical support and promotion - just as I was itching to start a new programme.

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James W. Black

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Brian Pritchard, clinical pharmacologist at University College, London, spearheaded the clinical development of the beta-adrenoceptor antagonists and crusaded on their behalf - as well as revolutionising their use by his discovery of their antihypertensive effect.

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James W. Black

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Bill Duncan joined me to run the Biochemistry Department, so maintaining a tremendously successful partnership which lasted 15 years.

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James W. Black

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As I slowly learned, like a primitive painter, how to be an effective experimenter, ideas began to ferment. Work with Adam Smith on the effects of 5-hydroxytryptamine on gastric acid secretion was to surface again later on in my interest in the pharmacology of histamine-stimulated acid secretion.

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