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James W. Black

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Yet despite disappointment in my managerial role, I made great progress in my own research. Working with brilliant young investigators such as Paul Leff, I began to see analytical pharmacology as a viable discipline.

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James W. Black

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Work with George Smith, concerned with finding ways of increasing the supply of oxygen to the heart in patients with narrowed coronary arteries, led me to propose that reducing myocardial demand for oxygen by annulling cardiac sympathetic drive might be equally effective.

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James W. Black

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When I was struggling at the front, Bill Duncan was defending the rear. Mike Parsons adopted the new pharmacology with rare enthusiasm and commitment and became one of the doughtiest colleagues I have ever had. I think we made a good team.

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James W. Black

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When I developed the technology to show that, in rats, iodoacetate rapidly and irreversibly reduced the blood pressure to about 40 mm Hg, I was faced with the question which has influenced my thinking ever since: when and to what extent does local blood flow act as a metabolic throttle?

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James W. Black

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Weipers gave me the opportunity to start a new Physiology Department, and during the next eight years I built a state-of-the-art physiology teaching laboratory based on my enduring belief that our brains work best when doing focuses our thinking.

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James W. Black

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We went to Singapore at the end of 1947 - an inevitable result of marriage, debts accumulated to pay for the completion of my medical studies, and pitiful academic prospects.

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James W. Black

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We paid off our debts, we learned some, made friends and returned in 1950 with a larger view of life. I had, however, no home, no income of any kind and no prospects whatsoever.

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James W. Black

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We had a daughter, Stephanie, born in 1951; I built a workshop-coupled research laboratory providing the most advanced cardiovascular technology I knew; and persuaded George Smith and Adam Smith, academic surgeons, to join me.

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James W. Black

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Undergraduate prizes seemed to confirm that I was working harder than my colleagues in a new-found love affair with knowledge.

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James W. Black

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The young aficionados of St Salvator's Hall in my day were culled from every imaginable class and state from the United Kingdom and overseas.

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