Steven Weinberg
The more the universe seems comprehensible, the more it also seems pointless.
The effort to understand the universe is one of the very few things that lifts human life a little above the level of farce, and gives it some of the grace of tragedy.
Maybe nature is fundamentally ugly, chaotic and complicated. But if it's like that, then I want out.
An expert is a person who avoids the small errors while sweeping on to the grand fallacy.